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Drosophila BEACH domain autophagic adaptor <i>blue cheese</i> shuttles between vesicle populations and is required for an early step in autophagy

2016-11-04

Abstract excerpt

Drosophila melanogaster blue cheese ( bchs ) encodes a large BEACH (Beige and Chediak-Higashi) family protein that is postulated to function as an adaptor protein with roles in vesicle trafficking. Mutation in bchs leads to the accumulation of ubiquitinated aggregates in aged brains, presumably because of a conserved function with its human homologue Autophagy-Linked FYVE (ALFY), which interacts with Atg5 and p6...

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Literature Corpus work
3fc9667b-e530-533a-bd2d-d2a65e0b3da4
DOI
10.1101/084434
Open publication

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Drosophila BEACH domain autophagic adaptor <i>blue cheese</i> shuttles between vesicle populations and is required for an early step in autophagyDOI 10.1101/084434
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