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Article

The Drosophila BEACH family protein, blue cheese, links lysosomal axon transport with motor neuron degeneration.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Jan 2009

Lim Angeline, Kraut Rachel

Abstract excerpt

Impaired axon transport is one of the earliest pathological manifestations of several neurodegenerative diseases, and mutations in motor proteins can exacerbate or cause degeneration (Williamson and Cleveland, 1999; Gunawardena and Goldstein, 2004; Stokin and Goldstein, 2006). Compromised function in lysosomes and other degradative organelles that intersect with the lysosomal pathway are also strongly implicated...

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Identifiers

PMID: 19176804
DOI: 10.1523/JNEUROSCI.2582-08.2009
PMCID: PMC3849423

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The Drosophila BEACH family protein, blue cheese, links lysosomal axon transport with motor neuron degeneration.PMID 19176804Read ↗

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