PCI-DB: A novel primary tissue immunopeptidome database to guide next-generation peptide-based immunotherapy development

Abstract excerpt

<title>Abstract</title> <p>Various cancer immunotherapies rely on the T cell-mediated recognition of peptide antigens presented on human leukocyte antigens (HLA). However, the identification and selection of naturally presented peptide targets for the development of personalized as well as off-the-shelf immunotherapy approaches remains challenging. Here, we introduce the open-access Peptides for Cancer Immunother...

Topics

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• Adenocarcinoma of Lung
• Antigens, Neoplasm
• ErbB Receptors
• Histocompatibility Antigens Class I
• Immunotherapy and Immune Responses
• Lung Neoplasms
• Monoclonal and Polyclonal Antibodies Research
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

08bd3a3f-d04c-5578-b5d3-93e973dece89

DOI

10.21203/rs.3.rs-5550116/v1