Article

Synthetic Cannabidiol Attenuates Heart Failure Progression with Concomitant and Post Injury Administration Through Modulation of Immune and Endothelial to Mesenchymal Transition – Related Remodeling Programs

2026-07-16

Abstract excerpt

<h4>Background</h4> Cardiac fibrosis is a central driver of adverse remodeling in heart failure with reduced ejection fraction (HFrEF), yet therapies directly targeting these pathways remain less established. We investigated the role of a pharmaceutical-grade synthetic (s) cannabidiol in HFrEF using an invitro and in vivo strategy. <h4>Methods</h4> HFrEF was induced in 12-week-old C57BL/6J mice using angiotensin...

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Literature Corpus work: 3e7a79e8-1d33-5646-99c1-2d3eb8cccb14
DOI: 10.64898/2026.07.10.737555

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