Article

Exercise-Induced Epoxy-Eicosanoids Promote Cardiomyocyte Proliferation and Post-Infarction Repair via NR4A1

2026-01-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Myocardial infarction (MI) causes irreversible cardiomyocyte loss that exceeds the adult heart’s regenerative capacity, leading to adverse remodeling and heart failure. While exercise provides cardiovascular protection, the mechanisms underlying exercise-induced cardiac repair remain unclear. <h4>METHODS</h4> Plasma levels of free fatty acids and polyunsaturated fatty acid...

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Literature Corpus work: cab171ca-ab32-5561-b5be-4b009c497810
DOI: 10.64898/2026.01.12.699155

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