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Article

From genome-wide association studies to functional genomics: new insights into cardiovascular disease.

The Canadian journal of cardiology - 1 Jan 2013

McPherson Ruth

Abstract excerpt

Genome-wide association studies (GWASs) for coronary artery disease (CAD) have identified more than 30 variants robustly associated with CAD risk. The majority are not associated with conventional risk factors but highlight novel pathways, including cellular proliferation. Although some risk variants are nonsynonymous coding variants resulting in an amino acid change in the encoded protein, the majority are in...

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Identifiers

PMID: 23200092
DOI: 10.1016/j.cjca.2012.08.017

Genes

CAD

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