Article

Integrative multi-ethnic Mendelian randomisation identifies tissue-specific causal genes for Coronary Artery Disease and interactions with post-acute Covid

2024-10-13

Abstract excerpt

<h4>ABSTRACT</h4> Coronary artery disease (CAD) is highly heritable and remains the leading cause of mortality worldwide. Understanding the genetic and mechanistic underpinnings of CAD is crucial for early risk assessment and intervention. We conducted a transcriptome-wide Mendelian randomisation (MR) study, utilising unbiased tissue-specific gene regulatory networks, to identify genes causally associated with CAD...

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Literature Corpus work: 2f8b6629-4f2e-5ec2-9435-feb002a56d24
DOI: 10.1101/2024.10.11.24315315

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