Article
Genetics of coronary artery disease in the post-GWAS era.
Journal of internal medicine - 1 Nov 2021
Chen Zhifen, Schunkert Heribert
Abstract excerpt
During the past decade, genome-wide association studies (GWAS) have transformed our understanding of many heritable traits. Three recent large-scale GWAS meta-analyses now further markedly expand the knowledge on coronary artery disease (CAD) genetics in doubling the number of loci with genome-wide significant signals. Here, we review the unprecedented discoveries of CAD GWAS on low-frequency variants,...
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