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Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review

2025-04-30

Abstract excerpt

Estimating heritability has been fundamental in understanding the genetic contributions to complex disorders like late-onset Alzheimer’s disease (LOAD), and provides a rationale for identifying genetic factors associated with disease susceptibility. While numerous studies have established substantial genetic contribution for LOAD, the interpretation of heritability estimates remains challenging. These challenges a...

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Literature Corpus work
3db22789-169b-5f22-b9cc-30dc6f48dd84
DOI
10.1101/2025.04.29.25326648
Open publication

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Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic reviewDOI 10.1101/2025.04.29.25326648
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