Article
The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.
Neurobiology of aging - 1 May 2016
Mez Jesse, Mukherjee Shubhabrata, Thornton Timothy, Fardo David W, Trittschuh Emily, Sutti Sheila, Sherva Richard, Kauwe John S, Naj Adam C, Beecham Gary W, Gross Alden, Saykin Andrew J, Green Robert C, Crane Paul K
Abstract excerpt
Late-onset Alzheimer's disease (LOAD) can present heterogeneously, with several subtypes recognized, including dysexecutive AD. One way to identify people with dysexecutive AD is to consider the difference between memory and executive functioning, which we refer to as the executive prominent/memory prominent spectrum. We aimed to determine if this spectrum was heritable. We used neuropsychological and genetic...
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