Article

Functional development of a V3-specific broadly neutralizing antibody isolated from a case of HIV superinfection

2021-03-17

Abstract excerpt

Stimulating broadly neutralizing antibodies (bnAbs) directly from germline remains a barrier for HIV vaccines. HIV superinfection elicits bnAbs more frequently than single infection, providing clues of how to elicit such responses. We used longitudinal antibody sequencing and structural studies to characterize bnAb development from a superinfection case. Mature bnAb QA013.2 bound both initial transmitted and super...

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Literature Corpus work: 3d468d97-b269-52cf-9a7e-3b34d44ff9a4
DOI: 10.1101/2021.03.15.435484

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