Article

CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions

2023-04-27

Abstract excerpt

<h4>Summary</h4> The sheer complexity of the brain has complicated our ability to understand the cellular and molecular mechanisms underlying its function in health and disease. Genome-wide association studies have uncovered genetic variants associated with specific neurological phenotypes and diseases. In addition, single-cell transcriptomics have provided molecular descriptions of specific brain cell types and...

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Literature Corpus work: 3d38347b-d23c-515d-a42b-6b05118deb11
DOI: 10.1101/2023.04.26.538498

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