Article

An Efficient Direct Conversion Strategy to Generate Functional Astrocytes from Human Adult Fibroblasts

2024-09-03

Abstract excerpt

<h4>Summary</h4> Direct reprogramming approaches offer an attractive alternative to stem-cell-derived models, allowing the retention of epigenetic information and age-associated cellular phenotypes, and providing an expedited method to generate target cell types. Several groups have previously generated multiple neuronal subtypes, neural progenitor cells, oligodendrocytes, and other cell types directly from fibro...

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Literature Corpus work: 99823f05-519d-5dff-b1c4-69545c591894
DOI: 10.1101/2024.09.02.610876

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