Article

Genetic Deletion of Skeletal Muscle Inositol Polyphosphate Multikinase Disrupts Glucose Homeostasis and Impairs Exercise Tolerance

2024-07-29

Abstract excerpt

Inositol phosphates are critical signaling messengers involved in a wide range of biological pathways in which inositol polyphosphate multikinase (IPMK) functions as a rate-limiting enzyme for inositol polyphosphate metabolism. IPMK has been implicated in cellular metabolism, but its function at the systemic level is still poorly understood. Since skeletal muscle is a major contributor to energy homeostasis, we ha...

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Literature Corpus work: 3d1f8e8d-2aca-50cb-a1c5-f871cdf2fa7b
DOI: 10.1101/2024.07.28.605526

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