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Article

Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases

27 Dec 2022

Abstract excerpt

Adequate mass and function of adipose tissues (ATs) play essential roles in preventing metabolic perturbations. The pathological reduction of ATs in lipodystrophy leads to an array of metabolic diseases. Understanding the underlying mechanisms may benefit the development of effective therapies. Several cellular processes, including autophagy and vesicle trafficking, function collectively to maintain AT...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 36574710
DOI: 10.1073/pnas.2214874120

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