Article

Glucose intolerance in aging is mediated by the Gpcpd1-GPC metabolic axis

2021-10-26

Abstract excerpt

Skeletal muscle plays a central role in the regulation of systemic metabolism during lifespan. With aging, muscle mediated metabolic homeostasis is perturbed, contributing to the onset of multiple chronic diseases. Our knowledge on the mechanisms responsible for this age-related perturbation is limited, as it is difficult to distinguish between correlation and causality of molecular changes in muscle aging. Glycer...

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Literature Corpus work: 1b31f22b-1115-5676-93bb-ad1579b50202
DOI: 10.1101/2021.10.26.465828

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