Article
Human MDSCs derived from the bone marrow maintain their functional ability but have a reduced frequency of induction in the elderly compared to pediatric donors
2020-09-02
Abstract excerpt
<title>Abstract</title> <p>Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immunosuppressive cells developing from myeloid progenitors, which are enriched in pathological conditions such as cancer, and are known to inhibit the functions of effector T cells. During aging, several changes occur both at the adaptive and innate immune system level, in a process defined as immunoscenescence....
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Identifiers and source
- Literature Corpus work
- 3d0084c4-6f9b-5960-b0a8-6cb9412a7701
- DOI
- 10.21203/rs.3.rs-39610/v3