Article
Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS
15 Jun 2021
Abstract excerpt
With a growing aged population, there is an imminent need to develop new therapeutic strategies to ameliorate disorders of hematopoietic aging, including clonal hematopoiesis and myelodysplastic syndrome (MDS). Cell-intrinsic dysregulation of innate immune- and inflammatory-related pathways as well as systemic inflammation have been implicated in hematopoietic defects associated with aging, clonal hematopoiesis,...
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