Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myeloid-Derived Suppressor Cells (MDSCs) at the Crossroad of Senescence and Cancer

4 Jul 2025

Abstract excerpt

The family of myeloid-derived suppressor cells (MDSCs) includes a heterogeneous group of partially immature cells belonging to the myeloid lineage with potent immunosuppressive functions. They might be increased in the peripheral blood of cancer patients and in the microenvironment of cancer lesions, where they act in suppressing adaptive and innate immune cells, promoting tumor progression, and facilitating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Immune cells in cancer
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40647547
DOI: 10.3390/cancers17132251

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myeloid-Derived Suppressor Cells (MDSCs) at the Crossroad of Senescence and CancerPMID 40647547Read ↗

The New Era of Cancer Immunotherapy: Targeting Myeloid-Derived Suppressor Cells to Overcome Immune Evasion.Semantic proximity Read ↗

Phenotypes, accumulation, and functions of myeloid-derived suppressor cells and associated treatment strategies in cancer patients.Semantic proximity Read ↗

Myeloid-Derived Suppressor Cells.Semantic proximity Read ↗

Myeloid derived suppressor cells in physiological and pathological conditions: the good, the bad, and the ugly.Semantic proximity Read ↗

Bone Marrow Senescence and the Microenvironment of Hematological MalignanciesSemantic proximity Read ↗

Blood CD33(+)HLA-DR(−) myeloid-derived suppressor cells are increased with age and a history of cancerSemantic proximity Read ↗

Myeloid-Derived Suppressor Cells: Immune-Suppressive Cells That Impair Antitumor Immunity and Are Sculpted by Their Environment.Semantic proximity Read ↗

Myelodysplastic syndromes, aging, and age: correlations, common mechanisms, and clinical implications.Semantic proximity Read ↗

Human MDSCs derived from the bone marrow maintain their functional ability but have a reduced frequency of induction in the elderly compared to pediatric donorsSemantic proximity Read ↗

Myeloid-Derived Suppressor Cells in Solid TumorsSemantic proximity Read ↗

Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapySemantic proximity Read ↗

Complexity and challenges in defining myeloid-derived suppressor cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.