Article
Myeloid derived suppressor cells in physiological and pathological conditions: the good, the bad, and the ugly.
Immunologic research - 1 Dec 2013
Serafini Paolo
Abstract excerpt
Myeloid derived suppressor cells (MDSCs), a heterogeneous population of myeloid progenitors, are recognized as a key element in tumor escape and progression. The importance of MDSCs in human malignancies has been demonstrated in recent years, and new approaches targeting their suppressive/tolerogenic action are currently being tested in both preclinical model and clinical trials. However, emerging evidence...
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