Article

Development of an efficient single-cell cloning and expansion strategy for genome edited induced pluripotent stem cells

2021-07-31

Abstract excerpt

Disease-specific human induced pluripotent stem cells (hiPSCs) can be generated directly from individuals with known disease characteristics or alternatively be modified using genome editing approaches to introduce disease causing genetic mutations to study the biological response of those mutations. The genome editing procedure in hiPSCs is still inefficient, particularly when it comes to homology directed repair...

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Literature Corpus work: 3c8e8aaf-9b2c-5525-8a4b-26327e0f4e10
DOI: 10.1101/2021.07.31.453934

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