Article

Highly efficient chondrogenic differentiation of human iPSCs and purification via a reporter allele generated by CRISPR-Cas9 genome editing

2018-01-24

Abstract excerpt

<h4>Summary</h4> The differentiation of human induced pluripotent stem cells (hiPSCs) to prescribed cell fates enables the engineering of patient-specific tissue types, such as hyaline cartilage, for applications in regenerative medicine, disease modeling, and drug screening. In many cases, however, these differentiation approaches are poorly controlled and generate heterogeneous cell populations. Here we demonst...

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Literature Corpus work: b5450905-b67b-5801-b988-de7cd3da4be8
DOI: 10.1101/252767

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