Article
A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals.
Stem cell reports - 14 Dec 2021
Schaniel Christoph, Dhanan Priyanka, Hu Bin, Xiong Yuguang, Raghunandan Teeya, Gonzalez David M, Dariolli Rafael, D'Souza Sunita L, Yadaw Arjun S, Hansen Jens, Jayaraman Gomathi, Mathew Bino, Machado Moara, Berger Seth I, Tripodi Joseph, Najfeld Vesna, Garg Jalaj, Miller Marc, Surlyn Colleen S, Michelis Katherine C, Tangirala Neelima C, Weerahandi Himali, Thomas David C, Beaumont Kristin G, Sebra Robert, Mahajan Milind, Schadt Eric, Vidovic Dusica, Schürer Stephan C, Goldfarb Joseph, Azeloglu Evren U, Birtwistle Marc R, Sobie Eric A, Kovacic Jason C, Dubois Nicole C, Iyengar Ravi
Abstract excerpt
A library of well-characterized human induced pluripotent stem cell (hiPSC) lines from clinically healthy human subjects could serve as a useful resource of normal controls for in vitro human development, disease modeling, genotype-phenotype association studies, and drug response evaluation. We report generation and extensive characterization of a gender-balanced, racially/ethnically diverse library of hiPSC...
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