Article

Evaluation of optimal methods and ancestries for calculating polygenic risk scores in East Asian population

2023-01-20

Abstract excerpt

Polygenic risk scores (PRSs) have been studied for predicting human diseases, and various methods for PRS calculation have been developed. Most PRS studies to date have focused on European ancestry, and the performance of PRS has not been sufficiently assessed in East Asia. Herein, we evaluated the best-performing PRSs for East Asian populations using data for seven diseases: asthma, breast cancer, coronary artery...

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Literature Corpus work: 3c1c997e-afea-5d5a-bf28-eb00ff0839c3
DOI: 10.21203/rs.3.rs-2489951/v1

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