Article

Assessment of polygenic risk score performance in East Asian populations for ten common diseases: A Korean cohort study

2024-08-26

Abstract excerpt

<title>Abstract</title> <p>Polygenic risk score (PRS) uses genetic variants to assess disease susceptibility. While PRS performance is well-studied in Europeans, its accuracy in East Asians is less explored. This study compared East Asian PRS-continuous shrinkage (PRS-CS) from single-population genome-wide association studies (GWAS) with transferability PRS (PRS-CSx) integrating European and East Asian GWAS for t...

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Literature Corpus work: 29b2e1da-b9ff-5a94-bafc-5a0250ae1716
DOI: 10.21203/rs.3.rs-4781909/v1

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