Article

Global biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

2021-11-21

Abstract excerpt

<h4>Summary</h4> With the increasing availability of biobank-scale datasets that incorporate both genomic data and electronic health records, many associations between genetic variants and phenotypes of interest have been discovered. Polygenic risk scores (PRS), which are being widely explored in precision medicine, use the results of association studies to predict the genetic component of disease risk by accumula...

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Literature Corpus work: b22e84f9-cd4e-5da7-a6d7-8f7e05a88d7d
DOI: 10.1101/2021.11.18.21266545

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