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[Polygenic risk score combined with traditional risk factors for assessing the risk of type 2 diabetes mellitus among Chinese adults].

Wei sheng yan jiu = Journal of hygiene research - 1 May 2026

Ou Lingling, Zhuo Qin, Han Chao, Chen Liangkai, Ju Lahong, Wang Huijun, Wang Mengtian, Shen Xin, Zhao Jinpeng, Li Yan

Abstract excerpt

OBJECTIVE: To evaluate the predictive ability of a polygenic risk score(PRS) combined with traditional risk factors for type 2 diabetes mellitus(T2DM) in Chinese adults. METHODS: Using data from the "China Adult Chronic Disease and Nutrition Surveillance(2015)" project, we conducted a case-control study comprising 2041 people with T2DM and 1149 healthy adults of same age as control group. Total DNA was extracted...

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PMID: 42394318
DOI: 10.19813/j.cnki.weishengyanjiu.2026.03.002

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