Article

A nucleolar stress gene signature for quantitative scoring across multi-omics contexts

2026-04-13

Abstract excerpt

The nucleolus is essential for ribosome biogenesis and cellular homeostasis, and its dysfunction can induce nucleolar stress, which has been implicated in cancer and other diseases. However, nucleolar stress is commonly inferred from morphological alterations or a limited set of functional assays, and quantitative approaches based on gene expression profiles remain lacking. Here, we integrate literature curation w...

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Literature Corpus work: 3b63263a-5338-5b5d-8233-0084793c8df9
DOI: 10.64898/2026.04.12.718053

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