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Article

The Wnt/β-Catenin Pathway is Activated as a Novel Nucleolar Stress Response.

Journal of molecular biology - 22 Jan 2021

Dannheisig David P, Bächle Jana, Tasic Jasmin, Keil Marina, Pfister Astrid S

Abstract excerpt

Ribosomes are mandatory for growth and survival. The complex process of ribosome biogenesis is located in nucleoli and requires action of the RNA polymerases I-III, together with a multitude of processing factors involved in rRNA cleavage and maturation. Impaired ribosome biogenesis and loss of nucleolar integrity triggers nucleolar stress, which classically stabilizes the tumor suppressor p53 and induces cell...

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Source

Identifiers

PMID: 33221336
DOI: 10.1016/j.jmb.2020.11.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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