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Article

Nucleolar Stress: hallmarks, sensing mechanism and diseases

5 Jun 2018

Abstract excerpt

The nucleolus is a prominent subnuclear compartment, where ribosome biosynthesis takes place. Recently, the nucleolus has gained attention for its novel role in the regulation of cellular stress. Nucleolar stress is emerging as a new concept, which is characterized by diverse cellular insult-induced abnormalities in nucleolar structure and function, ultimately leading to activation of p53 or other stress...

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PMID: 31225478
DOI: 10.15698/cst2018.06.139

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