Article

Robust analysis of comparative subcellular omics with complex designs

2026-07-07

Abstract excerpt

Subcellular omics technologies now allow us to obtain insights into steady-state localisation and re-localisation of biomolecules in high-throughput. However, robust analysis of these experiments can be slow and challenging. Here, we show that existing approaches to differential localisation fall into two classes, marker-dependent and marker-free, that fail for fundamentally different statistical reasons, with fai...

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Literature Corpus work: 88fc9045-04d6-5998-9cd0-a87bea028d4a
DOI: 10.64898/2026.07.07.736960

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