Article

Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole genome sequencing with histopathological features

2023-02-27

Abstract excerpt

<h4>ABSTRACT</h4> Extension of prostate cancer beyond the primary site into the surrounding organs by local invasion or nodal metastasis is associated with poor prognosis. The emergence and evolution of cancer clones at this early stage of expansion and spread has not been studied in detail. We performed whole genome sequencing on 42 prostate cancer samples from the prostate, seminal vesicles and regional lymph n...

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Literature Corpus work: 3afd0acc-67c7-59a2-b513-4a73dd0654a7
DOI: 10.1101/2023.02.27.530113

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Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole genome sequencing with histopathological featuresDOI 10.1101/2023.02.27.530113Read

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