Article
A Systematic Review of Prostate Cancer Heterogeneity: Understanding the Clonal Ancestry of Multifocal Disease.
European urology oncology - 1 Jun 2021
Erickson Andrew, Hayes Alicia, Rajakumar Timothy, Verrill Clare, Bryant Richard J, Hamdy Freddie C, Wedge David C, Woodcock Dan J, Mills Ian G, Lamb Alastair D
Abstract excerpt
CONTEXT: Studies characterising genomic changes in prostate cancer (PCa) during natural progression have greatly increased our understanding of the disease. A better understanding of the evolutionary history of PCa would allow advances in diagnostics, prognostication, and novel therapies that together will improve patient outcomes. OBJECTIVE: To review the molecular heterogeneity of PCa and assess recent efforts...
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