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Article

Genetic Progression of High Grade Prostatic Intraepithelial Neoplasia to Prostate Cancer.

European urology - 1 May 2016

Jung Seung-Hyun, Shin Sun, Kim Min Sung, Baek In-Pyo, Lee Ji Youl, Lee Sung Hak, Kim Tae-Min, Lee Sug Hyung, Chung Yeun-Jun

Abstract excerpt

BACKGROUND: Although high grade prostatic intraepithelial neoplasia (HGPIN) is considered a neoplastic lesion that precedes prostate cancer (PCA), the genomic structures of HGPIN remain unknown. OBJECTIVE: Identification of the genomic landscape of HGPIN and the genomic differences between HGPIN and PCA that may drive the progression to PCA. DESIGN, SETTINGS, AND PARTICIPANTS: We analyzed 20 regions of paired...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26542946
DOI: 10.1016/j.eururo.2015.10.031

Genes

FOXA1
SPOP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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