Article
Translational and clinical implications of the genetic landscape of prostate cancer.
Nature reviews. Clinical oncology - 1 Oct 2016
Spratt Daniel E, Zumsteg Zachary S, Feng Felix Y, Tomlins Scott A
Abstract excerpt
Over the past several years, analyses of data from high-throughput studies have elucidated many fundamental insights into prostate cancer biology. These insights include the identification of molecular alterations and subtypes that drive tumour progression, recurrent aberrations in signalling pathways, the existence of substantial intertumoural and intratumoural heterogeneity, Darwinian evolution in response to...
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