Article
Leaky scanning translates a conserved ORF in the 3′UTR of RPL36A and regulates the expression of ribosomal protein L36a.
2026-05-29
Abstract excerpt
The 3′UTRs of eukaryotic mRNAs are major hubs of post-transcriptional regulation that govern the spatial and temporal regulation of gene expression. Although 3′UTRs were long considered non-coding, recent studies have revealed translation within downstream open reading frames (dORFs) located in 3′UTRs. In contrast to upstream ORFs (uORFs) in 5′UTRs, the mechanisms governing dORF translation and their functional si...
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Identifiers and source
- Literature Corpus work
- 3a5d2a25-80f4-5ace-abe3-be1c2d8f0cd1
- DOI
- 10.64898/2026.05.26.727855
