Article

<i>uORF-Tools</i> – Workflow for the determination of translation-regulatory upstream open reading frames

2018-09-13

Abstract excerpt

Ribosome profiling (ribo-seq) provides a means to analyze active translation by determining ribosome occupancy in a transcriptome-wide manner. The vast majority of ribosome protected fragments (RPFs) resides within the protein-coding sequence of mRNAs. However, commonly reads are also found within the transcript leader sequence (TLS) (aka 5’ untranslated region) preceding the main open reading frame (ORF), indicat...

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Literature Corpus work: 9fc53dd1-b4b5-5e51-8b67-0b98946bafe0
DOI: 10.1101/415018

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