Article

Mechanisms Leading to the Loss of AUG Codon Function as a Translation Initiator

2025-06-11

Abstract excerpt

The AUG codon represents the canonical start site for translation initiation in eukaryotic cells, yet its proper function can be disrupted by a variety of regulatory mechanisms. In this review, conducted between April and June 2025, we comprehensively examined the most recent literature to identify key modulators that impair AUG-mediated initiation. These include suboptimal nucleotide contexts (e.g., weak Kozak co...

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Literature Corpus work: 3858b7f3-bf62-59bd-91b0-18ef2ac763e4
DOI: 10.20944/preprints202506.0820.v1

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