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Requirement for oxidation of neuronal ketone bodies in aging and neurodegeneration

2026-03-27

Abstract excerpt

Glucose is the brain’s primary fuel, but the brain can also use alternative energy substrates, especially during development or starvation. Emerging evidence suggests ketone metabolism may help the brain adapt to energy stress in neurodegenerative diseases such as Alzheimer’s disease, although its role in constitutive brain function in normal aging is poorly understood. Using iPSC-derived human neurons and adult-i...

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Literature Corpus work
a344b931-f742-50bd-b0cf-a9fc4969f49d
DOI
10.64898/2026.03.24.712448
Open publication

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Requirement for oxidation of neuronal ketone bodies in aging and neurodegenerationDOI 10.64898/2026.03.24.712448
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