Article

Differential modularity of the mammalian <i>Engrailed 1</i> enhancer network directs eccrine sweat gland development

2022-09-17

Abstract excerpt

<h4>Summary</h4> Enhancers are context-specific regulators of expression that drive biological complexity and variation through the redeployment of conserved genes. An example of this is the enhancer-mediated control of the transcription of Engrailed 1 ( EN1 ), a pleiotropic gene whose expression is required for the specification of eccrine sweat glands in mammals. We have previously identified an enhancer, ECE...

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Literature Corpus work: 39e1a13c-cf1b-5141-aad0-49dbb28abd00
DOI: 10.1101/2022.09.14.508033

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