Article
Pleiotropic enhancers are ubiquitous regulatory elements in the human genome
2022-01-25
Abstract excerpt
Enhancers are regulatory elements of genomes that determine spatio-temporal patterns of gene expression. The human genome contains a vast number of enhancers, which largely outnumber protein-coding genes. Classically, enhancers have been regarded as highly tissue-specific. However, recent evidence suggests that many enhancers are pleiotropic, with activity in multiple developmental contexts. Yet, the extent and im...
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Identifiers and source
- Literature Corpus work
- 91acde0d-e084-5a89-bc4f-6097680b193a
- DOI
- 10.1101/2022.01.25.477532