Article

A transient dermal niche and dual epidermal programs underlie sweat gland development

2023-04-17

Abstract excerpt

Eccrine glands are mammalian skin appendages indispensable for human thermoregulation. Like all skin-derived appendages, eccrine glands form from multipotent progenitors in the basal skin epidermis. It remains unclear how epidermal progenitors progressively specialize to specifically form eccrine glands, precluding efforts to regenerate these vital organs. Herein, we applied single nucleus transcriptomics to compa...

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Literature Corpus work: 0f095871-8bde-5e60-8d45-1b4946a6efb3
DOI: 10.1101/2023.04.15.537037

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