Article

Variation in APOE ε4 Prevalence and Brain Health Associations by European Descent in White All of Us Participants

2025-07-17

Abstract excerpt

<h4>Importance</h4> The APOE ε4 allele is among the best-established genetic risk factor for Alzheimer’s disease. Different ethnic and racial groups have varying APOE ε4 prevalences. The prevalence of APOE ε4 also varies among European regions, yet White Americans are treated as a monolith, potentially impacting recruitment decisions and risk profile estimations. <h4>Objective</h4> To test whether White American...

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Literature Corpus work: 399d852f-28c3-5215-b5a5-9f2fb062845e
DOI: 10.1101/2025.07.16.25331679

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