Article

Phenome-Wide Association of<i>APOE</i>Alleles in the<i>All of Us</i>Research Program

2024-09-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Genetic variation in APOE is associated with altered lipid metabolism, as well as cardiovascular and neurodegenerative disease risk. However, prior studies are largely limited to European ancestry populations and differential risk by sex and ancestry has not been widely evaluated. We utilized a phenome-wide association study (PheWAS) approach to explore APOE - associated pheno...

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Literature Corpus work: f522cee8-98ec-5d83-a0d8-05e4d703003d
DOI: 10.1101/2024.09.04.24313010

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