Article
The Proportion of APOE4 Carriers Among Non-Demented Individuals: A Pooled Analysis of 389,000 Community-Dwellers.
Journal of Alzheimer's disease : JAD - 1 Jan 2021
Wang Ya-Yu, Ge Yi-Jun, Tan Chen-Chen, Cao Xi-Peng, Tan Lan, Xu Wei
Abstract excerpt
BACKGROUND: The apolipoprotein E epsilon 4 (APOE4) is the strongest genetic risk factor for sporadic Alzheimer's disease (AD). Its carriage percentage in non-demented population varies across geographic regions and ethnic groups. OBJECTIVE: To estimate the proportion of APOE4 (2/4, 3/4, or 4/4) carriers in non-demented community-dwellers. METHODS: PubMed, EMBASE, and China National Knowledge Infrastructure were...
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