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Article

Variation in APOE ε4 Prevalence and Associations With Dementia-Related Outcomes by European Descent Among White Americans.

Alzheimer disease and associated disorders - 1 Jan 2025

Perales-Puchalt Jaime, Mansel Clayton O, Veatch Olivia J

Abstract excerpt

We tested whether White Americans of Southern European descent (AmEuro-S) have a lower APOE ε4 prevalence than their Northern European descent peers (AmEuro-N), and if APOE ε4-dementia-related outcome associations vary by European descent. We used secondary cross-sectional data from a US-based large cohort study. Using logistic regression, we compared the prevalence of APOE ε4 alleles among White Americans who...

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Identifiers

PMID: 41098071
DOI: 10.1097/WAD.0000000000000693
PMCID: PMC12626174

Genes

APOE

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