Article

Tissue-specific responses of brain and lung endothelial cell miRNA and mRNA profiles to the ring-stage Plasmodium falciparum-infected red blood cells

2024-04-08

Abstract excerpt

<title>Abstract</title> MicroRNAs (miRNAs) control 60% of genes expressed in the human body, but their role in malaria pathogenesis is incompletely understood. For the first time, we demonstrate cell type-specific alterations to the miRNA profiles during the early response to malaria infection in brain and lung endothelial cells (ECs). In brain ECs, incubation with <italic>Plasmodium falciparum</italic>-infect...

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Literature Corpus work: 39172456-6c45-5c9c-aef3-c0a8b374fa83
DOI: 10.21203/rs.3.rs-4222036/v1

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