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Plasmodium falciparum infection reshapes the human microRNA profiles of red blood cells and their extracellular vesicles

16 Jun 2023

Abstract excerpt

Plasmodium falciparum , a human malaria parasite, develops in red blood cells (RBCs), which represent approximately 70% of all human blood cells. Additionally, RBC-derived extracellular vesicles (RBC-EVs) represent 7.3% of the total EV population. The roles of microRNAs (miRNAs) in the consequences of P. falciparum infection are unclear. Here, we analyzed the miRNA profiles of non-infected human RBCs (niRBCs),...

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PMID: 37534175
DOI: 10.1016/j.isci.2023.107119

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