Article

The promoter mutation paucity as part of the dark matter of the cancer genome

2024-06-04

Abstract excerpt

Cancer is a heterogeneous disease caused by genetic alterations. Computational analysis of cancer genomes led to the expansion of the catalog of driver mutations. While individual high-impact mutations have been discovered also in gene promoters, frequency-based approaches have only characterized a few novel candidates. To investigate the promoter mutation paucity in cancer, we developed the REMIND-Cancer workflow...

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Literature Corpus work: 38dd9573-93f1-5038-b1ff-72d7af22626d
DOI: 10.1101/2024.06.03.597231

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