Article

A Pan-Cancer Transcriptome Analysis Reveals Pervasive Regulation through Tumor-Associated Alternative Promoters

2017-08-15

Abstract excerpt

<h4>ABSTRACT</h4> Most human protein-coding genes are regulated by multiple, distinct promoters, suggesting that the choice of promoter is as important as its level of transcriptional activity. While the role of promoters as driver elements in cancer has been recognized, the contribution of alternative promoters to regulation of the cancer transcriptome remains largely unexplored. Here we infer active promoters u...

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Literature Corpus work: a90c9db3-69d7-5501-8f30-6b31c4bcceb8
DOI: 10.1101/176487

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